Thomas Fireheart was born to parents of Native American descent, from the Kisani tribe. His parents were immigrants from Mexico, who lived in New York City. Thomas was born in New York City, a few months after his parents immigrated.
After graduating from high school, he went into the military, and years later, was a navy seal. At the age of 38, he left the military, and was hired by The Kingpin as an assassin to kill Spider-Man. He put up a good fight, but failed. Afterwards, he was found trapped in webbing by a mysterious man in a black trenchcoat and hat, who freed him. He was taken to the Kingpin and injected with a serum which was combined with Spider-Man's DNA, a puma's DNA, and a super soldier serum created by HYDRA. He was transformed into a super powered puma humanoid and called himself "Puma".
Puma fought Spider-Man a second time and Spider-Man, almost defeated and injured by Puma, luckily tazed Puma and did a pressure point on him, knocking him out. Puma reverted to his Human form and was found tied up by webbing, unconcious, by police officers. He was incarcerated.