Natalia Romanova, also known as Spider-Woman and Jessica Drew, was a member of the Red Room project in her native Russia. She was the only member who survive every training session and passed every test. As such, she was injected with a serum based on that of the Super-Soldier Serum and the spider-serum that empowered Peter Parker. She was sent to America to assassinate Nick Fury and infiltrate the hero community as Arachne, but she defied her former masters publicly. Now having gone rogue, Natalia adopted the new name of Jessica Drew and the alias of Spider-Woman.