Sinister Six (Earth-H2X0)

The Frightful Four are the main foes of the Superb Six.

Leader
Doctor Victor von Doom, ruler of Latveria

Co-Leader
Bentley Wittman, the Wizard, Tech savvy super villain.

Powerhouse
Venom, The alien symbiote of a spider, current host is unknown

Miscellaneous
Blastaar, a space monster composed of Laser energy.