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S.H.I.E.L.D.
S.H.I.E.L.D. (an acronym for Strategic Homeland Intervention, Enforcement and Logistics Division) is an espionage and law-enforcement agency. It's capital ship is a heavily modified aircraft carrier called the Hellicarrier (numbered 64), one of which also serves as Nick Fury's base of operations. SHIELD's primary headquarters is at the Triskelion. The S.S.R. (Strategic Scientific Reserve), formerly a top secret Allied way agency during World War II, now serves as the scientific division of SHIELD.


 * Colonel Nicholas Joseph "Nick" Fury: Executive Director of SHIELD, it was Nick Fury who had long planned the "Avengers Initiative" and set it into motion sometime after the Fantastic Four's debut. Based on the Earth-616 version.
 * Nicholas Joseph "Nick" Fury, Jr. aka Marcus Johnson: Son of Nia Johnson and Nick Fury, one of many unknown number of Fury's sons. He's a combination of his Earth-616 counterpart; and the Ultimate Marvel, Wolverine &amp; The X-Men/Avengers: EMH, 2010s Marvel Animated Universe and MCU versions of Nick Fury.
 * Commander Maria Hill: Deputy director. She's a combination of the Earth-616, Avengers: EMH, and the MCU versions.
 * Phillip J. "Phil" Coulson: Field officer who oversees many of the division's field operations, and a fan of Captain America. He's a combination of the MCU, Earth-616, and 2010s Marvel Animated Universe versions.
 * Melinda Qiaolian May/Calvary
 * Daisy "Skye" Johnson/Quake
 * Fitz-Simmons
 * Leopold "Leo" Fitz
 * Jemma Simmons
 * Sharon Carter/Agent 13: Field agent and girlfriend of Captain America.
 * Victoria Louise Hand

Former members

 * Colonel Chester Richards Phillips: He was one of the army officers overseeing subject selection for Project: Rebirth. He takes a personal interest in Steve Rogers as the best candidate for the first test.
 * Abraham Erskine (alias Josef Reinstein): A German scientist who defected to the United States. He created the Super-Soldier Serum for Project: Rebirth for the U.S. Army. He was shot by Nazi assassin Heinz Kruger soon after Steve was given the serum.
 * Agent Margaret "Peggy" Carter: Great-aunt of Sharon Parker, former S.S.R. agent and former lover of Captain America.

Howling Commandos
The Howling Commandos were a World War II elite combat unit led by Captain America.


 * Steve Rogers/Captain America: see Avengers
 * Sergeant James Buchanan "Bucky" Barnes: see Avengers
 * Captain Nick Fury: see S.H.I.E.L.D.
 * James "Logan" Howlett: see X-Men
 * Corporal Timothy Aloysius Cadwallader "Dum-Dum" Dugan
 * Private Isadore "Izzy" Cohen
 * Private Gabriel "Gabe" Jones
 * Private Dino Manelli
 * Private Robert "Rebel" Ralston
 * Private Jonathan "Junior" Juniper
 * Private Percival "Pinky" Pinkerton: British man.
 * Private Eric Koening: A defector from Nazi Germany. Initially was greeted with distrust from the team, especially Dum Dum.
 * Private Jim Morita: Japanese-American man.
 * Jacques "Frenchie" Dernier: A French man who was part of the French Resistance.
 * Lieutenant James Montgomery Falsworth: Another British man.

Avengers
The Avengers are among Earth's mightiest heroes. They first came together when Loki first brought the Chitauri to Earth.


 * Founders
 * Steven "Steve" Rogers/Captain America
 * Anthony "Tony" Stark/Iron Man
 * HELEN (Highly Elevated Logistic Experimental Network)
 * HOMER (Heuristically Operative Matrix Emulation Rostrum)
 * JARVIS (Just A Rather Very Intelligent System)
 * Thor Odinson
 * Dr. Bruce Banner/Hulk
 * Dr. Jonathan Henry "Hank" Pym/Ant-Man/Giant-Man
 * Janet van Dyne/Wasp


 * Additional members
 * Natasha Romanoff/Black Widow: A former KGB spy and assassin known as "the most dangerous woman in Europe", now a S.H.I.E.L.D. agent. She joins the Avengers to make amends for her betrayal. She's the only Avenger that Hulk can trust with the ability to kill him if he should go rogue. She's a combination of the Earth-616, MCU, Avengers: EMH, Marvel Anime, and 2010s Marvel Animated Universe versions.
 * Jennifer "Jen" Walter/She-Hulk
 * Clint Barton/Hawkeye
 * Barbara "Bobbi" Morse/Mockingbird
 * James Buchanan "Bucky" Barnes/Winter Soldier
 * Lt. Colonel James Rupert "Rhodey" Rhodes/War Machine/Iron Patriot
 * Sam Wilson/Falcon
 * Pietro Maximoff/Quicksilver: Twin brother of Wanda Maximoff, son of Magneto.
 * Wanda Maximoff/Scarlet Witch: Twin sister of Pietro Maximoff, daughter of Magneto.
 * "Victor Shade"/Vision: A "synthezoid" programmed by the evil A.I. Ultron to destroy the Avengers. But was reprogrammed by the combined geniuses of Tony Stark and Bruce Banner and imparted with the ability to fly, project intense engery beams and change the density of his form, the Vision has proved himself a worthy hero, aiding the Avengers in their struggle against Ultron.
 * T'Challa Udaku/Black Panther: The ruler and protector of Wakanda.
 * Carol Susan Jane Danvers/Ms. Marvel/Captain Marvel
 * Greer Grant Nelson/Tigra
 * Doreen Green/Squirrel Girl: A mutant girl who can communicate with squirrels. She's best friends with Pixie of the X-Men.
 * Monkey Joe
 * Tippy-Toe

X-Men
The X-Men are based at the Xavier's School for Gifted Youngsters.


 * Founders
 * Professor Charles Francis Xavier/Professor X: The world's most powerful telepath and a world-famous lecturer for pacifism and mutant emancipation. He's a combination of his Earth-616, 90s X-Men cartoon, and Movie counterparts.
 * Scott Summers/Cyclops
 * Jean Grey-Summer/Marvel Girl/Phoenix
 * Dr. Henry Philip "Hank" McCoy/Beast
 * Robert Louis "Bobby" Drake/Iceman
 * Warren Kenneth Worthington III/Angel


 * Additional members


 * James "Logan" Howlett/Wolverine
 * Ororo Munroe/Storm
 * Remy Etnne LeBeau/Gambit
 * Anna Marie Carlyle/Rogue
 * Kurt Wagner/Nightcrawler
 * Piotr Nikolaievitch "Peter" Rasputin/Colossus
 * Katherine Anne "Kitty" Pryde/Shadowcat: An upbeat and cheerful valley girl and a straight A student. She has the ability to phase through solid objects, which she manifested when she was 14. She's a combination of her Earth-616, X-Men: Evolution, and Wolverine and the X-Men counterparts.
 * Jubilation Lee/Jubilee
 * Elizabeth "Betsy" Braddock/Psylocke
 * Emmeline Grace "Emma" Frost: Originally the White Queen of the Hellfire Club, now an X-Men. She's a strong and powerful mutant telepath and empath, with the ability to shift into a solid, hardened diamond form. She developed romantic feelings for Cyclops. She's a combination of the Earth-616, Ultimate Marvel, and Wolverine and the X-Men versions.
 * James Arthur "Jamie" Madrox/Multiple: An extremely clumsy boy, who's frequent pratfalls often triggering his powers. He's the youngest of the team after Kitty, being the age of 12. He also has a crush on Kitty.  Based on the X-Men: Evolution version.
 * Alison Blaire/Dazzler
 * Kevin Sydney/Morph: A mutant with the ability to shape shift, and a close friend of Wolverine who claimed only Morph could make him laugh. Based on his 90s X-Men cartoon counterpart.
 * Megan Gwynn/Pixie: A mutant girl resembling a fairy. She likes being barefoot, though she often wears sandals. She's best friends with Squirrel Girl.
 * Victor "Vic" Borkowski/Anole: A homosexual boy with reptilian mutation. He looks up to Northstar of Alpha Flight, another gay mutant.


 * Others
 * Dr. Moira Kinross MacTaggert: A CIA agent turned geneticist who befriended Charles Xavier and Erik Lehnsherr.
 * Lockheed: Shadowcat's alien dragon friend who was exiled on Earth.

Fantastic Four
The Fantastic Four are four humans who received their powers after being exposed to a cosmic storm.


 * Reed Richards/Mister Fantastic
 * Susan "Sue" Storms Richards/Invisible Woman
 * Jonathan Lowell Spencer "Johnny" Storm/Human Torch
 * Benjamin Jacob "Ben" Grimm/Thing


 * Others
 * Franklin Benjamin Richards: Reed and Sue's son.
 * Roberta: The robot receptionist for the Fantastic Four in the Baxter Building. Her appearances is that of a young blue-eyed blonde woman with glasses in a business suit.
 * H.E.R.B.I.E. (Humanoid Experimental Robotic B-Type Integrated Electronics): A cheery supercomputer that monitors Reed's lab and the entirety of the security system for the Baxter Building. He has small, hovering helper robots as extensions of his computer core. He also acts as a nanny and a "big brother" friend to Reed and Sue's son Franklin. He can be high-strung and even neurotic at times, but he is also capable of level-headed thought and quick action in an emergency.

Guardians of the Galaxy
The Guardians of the Galaxy are a team of misfits from space who joined together as a team.


 * Peter Jason Quill/Star-Lord: The half-human, half-alien leader of the Guardians who was abducted from Missouri as a child and raised by a group of alien thieves and smugglers called the Ravagers.
 * Gamora: An orphan from an alien world who seeks redemption for her past crimes. She was adopted by Thanos and trained to be his personal assassin.
 * Drax the Destroyer: A warrior in search of vengeance against Ronan for killing his family.
 * Rocket Raccoon: A genetically engineered raccoon who is a bounty hunter and mercenary, as well as a master of weapons and battle tactics.
 * Groot: He is Groot, a tree-like humanoid who is the accomplice of Rocket.

Nova Empire

 * Xandarian Worldmind: A sentient supercomputer, whose data is entirely comprised of the experiences, histories, and personalities of deceased members of the Nova Corps as well as the general populace of Xandar. It is tasked with preserving itself (as it is one of the most knowledgable supercomputers in the universe) and acting as the custodian of the Nova Force.

Nova Corps
The Nova Corps are the planet Xandar's military/police force.


 * Nova Prime Irani Rael: A Rigellian who was secretly recruited by the Xandarian Worldmind.
 * Corpsman Rhomann Dey
 * Denarian Garthan Saal/Supernova

Big Hero 6
Big Hero 6 are a team of young superheroes.


 * Hiro Hamada
 * Baymax
 * Wasabi
 * Honey Lemon
 * GoGo Tomago
 * Fred

Inhumans
The Inhumans are a race of superhumans.


 * Inhuman Royal Family:
 * Blackagar Boltagon/Black Bolt: Leader of the Inhumans.
 * Medusalith Amaquelin Boltagon/Medusa: Queen of the Inhumans and wife of Black Bolt.
 * Crystalia Amaquelin Maximoff/Crystal
 * Gorgon
 * Karnak
 * Triton
 * Lockjaw: A dog-like being with teleportation powers.

Stark Industries
Stark Industries is a company who worked with the military, owned by Tony Stark.


 * Howard Stark: Tony's father, he worked on various government projects dating back to World War II, and was one of the founders of S.H.I.E.L.D..
 * Maria Stark (née Collins Carbonell/Cerra): Tony's mother. She was one of many dancing girls Stark hired in his many presentations.
 * Edwin Jarvis: Howard Stark's butler, and later served Tony.
 * Virginia Patricia "Pepper" Potts: Tony Stark's secretary/personal aide, and is virtually the only real friend he has at the company.
 * Harold "Happy" Hogan: Tony Stark's former bodyguard and chauffer, now head of security.

Roxxon Oil Corporation

 * Huge Jones: President of the Roxxon Oil Corporation who was once friends with Howard Stark.

Asgardians
The Asgardians are the inhabitants of Asgard. They are a race of human-like beings possessing a highly advanced form of technology resembling magic and sorcery, which their entire civilization is built up by. They are ruled by Odin, and seek to keep the peace between the Nine Realms of Yggdrasil. They are a brave and a powerful warrior race whose passion for adventure is their religion, but their isolationist society condemns them willingly to only the Nine Realms, making appearances from the Asgardians beyond Yggdrasil quite rare. Like the Vikings of Earth/Midgard, they believe that the only way to gain access into Valhalla (heaven) is to die in a glorious battle.


 * Bor: Former ruler of Asgard, Bor was Odin's father and Thor's grandfather.
 * Odin Borson: Current ruler of Asgard, Odin is the father of Thor and adoptive father of Loki.
 * Frigga: Wife of Odin, queen of Asgard, stepmother of Thor, and adoptive mother of Loki.
 * Heimdall: The all-seeing, all-hearing Asgardian sentry of the Bifrost Bridge.
 * Tyr
 * Eir: Asgardian physician.
 * Sif
 * Warriors Three: A group of three Asgardian adventurers who are among Thor's closest comrades.
 * Fandral the Dashing: Known to be an irrepressible swashbuckler and romantic.
 * Volstagg the Valiant: Known for his appetite and wide girth.
 * Hogun the Grim: A native of Vanaheim, Hogun is identified by his grim demeanor.
 * Destroyer: The Destroyer is a giant semi-autonomous being. It obeys the direct command of the King of Asgard. Its main function is to protect Odin's chamber of relics.
 * Lorelei

Yashida Zaibatsu
Yashida Zaibatsu is a technology development company that was formed at some point after World War II by Mariko Yashida's grandfather Ichirō Yashida.


 * Mariko Yashida
 * Yukio: A young mutant who can foresee the deaths of people, and was adopted by the Yashida family as a companion for Mariko when she was a little girl.
 * Black Clan


 * Former Members
 * Shingen Yashida: The father of Mariko Yashida.

Celestials
The Celestials are beings of energy encased in armor composed of vibranium, a metal with properties that prevent their dissipation. They are the creators of the legendary Black Monolith.


 * Eson the Searcher: A Celestial tasked with "seeking". It is presumed he's the grandfather of Star-Lord.

Culver University

 * Dr. Erik Selvig: A brilliant Professor of Theoretical Astrophysics.
 * Jane Foster: An astrophysicist who also had some nurse training. She was one of the few people that was convinced Thor really was the thunder god. She has a heroic personality, which is why Thor felt so amazed by her.
 * Darcy Lewis: A political science student.
 * Ian Boothby: Darcy's boyfriend.
 * Dr. Donald J. Blake: Thor's human host, a brilliant physician and Jane's ex-boyfriend.

Others

 * Elizabeth "Betty" Ross: Bruce's girlfriend/co-researcher, and the estranged daughter of General "Thunderbolt" Ross.
 * Richard Milhouse "Rick" Jones: A teenage orphan boy who becomes a faithful sidekick of the Hulk, after feeling responsible for Bruce's condition. He has blond hair and blue eyes, and wears a cowboy hat. He drives a motorcycle. He's a combination of the Earth-616, 1982 Incredible Hulk, Marvel Action Hour, and Iron Man: Armored Adventures.
 * Marlo Chandler: Rick Jone's crush.
 * Dr. Leonard "Leo" Samson
 * Dr. Stephen Vincent Strange
 * Peter Benjamin Parker/Spider-Man
 * Uncle Benjamin "Ben" Parker
 * Aunt May Parker (née Reilly)
 * Emily Osborn
 * Harold Theopolis "Harry" Osborn: Son of Norman Osborn and Peter Parker's best friend.
 * Bernard Houseman: The Osborn family butler.
 * Mary Jane Watson: Peter Parker's girlfriend. Called "MJ" by her friends, one of the most popular girls in high school and seemingly always in a good mood. Despite her sunny exterior, MJ has many insecurities that even her closest friends are unaware of. She's a combination of the Earth-616, Spider-Man: TAS, Spider-Man: TNAS, Ultimate Marvel, Spider-Man Loves Mary Jane and Spectacular Spider-Man versions.
 * Anna Watson: Mary Jane's paternal aunt and an old friend of Aunt May. She often suspicious with Peter's long absences and unreliability. She's a combination of the Earth-616 and Spider-Man: TAS versions.
 * George Stacy: Captain of the NYPD.
 * Helen Stacy: A successful lawyer.
 * Philip Stacy
 * Howard Stacy
 * Simon Stacy
 * Gwendolyne Maxine "Gwen" Stacy: A transfer student who became MJ's best friend. Gwen quickly becomes attached to Peter and starts dating him, becoming Mary Jane's rival for his affections. She's a combination of the Earth-616, Spider-Man Loves Mary Jane, and Amazing Spider-Man movie versions.
 * Debra Whitman: An intelligent and shy girl who is one of Peter Parker's best friends. She's a combination of the Earth-616 and Spider-Man: TAS versions, with Spectacular Spider-Man Gwen Stacy added to the mix.
 * Eugene Frederick "Flash" Thompson: A football player in high school and Liz's boyfriend. He has a tendency to bully the timid Peter Parker.
 * Clifford Kenneth "King Kong" McFarlane-Harlan: Best friend of Flash Thompson, and on the high school football team. He is of Asian descent. He crushed the spider that bit Peter. He eventually figured out Peter is Spider-Man, this knowledge and Peter's heroism inspired him to be a better person. He's a combination of the Ultimate Marvel and Spectacular Spider-Man versions.
 * Randolph "Randy" Robertson: He is on the Midtown High School football team with Flash Thompson. Based on the Spectacular Spider-Man version.
 * Elizabeth "Liz" Allan: One of the most popular girls in high school. She's a combination the Earth-616 version and Spider-Man: TAS Felicia Hardy, and some resemblance to the Spectacular Spider-Man Sally Avril.
 * Sally Avril: A cheerleader and Liz's ditzy and feisty best friend. She is Hispanic. Sally tends to be very bossy and self-centered, which puts a strain on her relationships with Randy and Liz. She also has a phobia of mutants (in particular) and super-powered beings (in general), and she worries she might become one. She's a combination of her Chapter One and Spectacular Spider-Man counterparts, Spider-Man Loves Mary Jane Liz Allan, and some resemblance to the Spectacular Spider-Man Liz Allan.
 * Gloria "Glory" Grant: Kenny Kong's on-and-off girlfriend. Based on the Spectacular Spider-Man version.
 * Carlie Cooper: A bespectacled girl who is in Peter's Science Club. She and Debra are best friends. She's a combination of her Earth-616 counterpart and the 2002 Spider-Man novelization version of Liz Allan.
 * Felicia Hardy/Black Cat: A teenager who transfers to the same high school attended by Peter Parker and Mary Jane Watson. She's also a thief, carrying the tradition of her father, the world-renowned cat-burglar Walter Hardy. Felicia is considered "bad luck" due to her violent past and confrontational personality. She flirts with Flash, but has stronger feelings for Spider-Man. She always challenges Sally to a fight. She's a combination of the Earth-616, Ultimate Marvel, Spider-Man Loves Mary Jane and Spectacular Spider-Man versions, with a bit of Ultimate Marvel Gwen Stacy added to the mix.
 * Angelica Jones/Firestar: She's a combination of the Spider-Man and his Amazing Friends and Earth-616 versions.
 * Ms. Lion: Angelica's pet dog. Aunt May often takes care of her.
 * Jean DeWolff: Police detective.
 * Terri Lee: Police lieutenant and DeWolff's partner.
 * J. Jonah Jameson: Publisher of the Daily Bugle, who views Spider-Man as a menace.
 * Joseph "Robbie" Robertson: Randy's father and editor of the Daily Bugle.
 * Elizabeth "Betty" Brant: J. Jonah Jameson's loyal secretary.
 * Dr. Nicholas Bromwell: A physician. Amongst his patients were May Parker and Peter Parker. He and Aunt May started dating. He's a combination of his Earth-616 counterpart and Ultimate Marvel Miles Warren.
 * Cassandra Webb/Madame Web: A blind, psychic, paraplegic mutant that acts as a cryptic adviser to Spider-Man, offering him strange clues and riddles that would ultimately help him. She's a combination of the Earth-616, Ultimate Marvel, and Spider-Man: TAS versions.
 * Matthew Michael "Matt" Murdock/Daredevil: A young man blinded as a boy but gifted with extraordinary senses, Matt dedicates his life to fight injustice in New York City as a lawyer by day, and as a superhero known as Daredevil by night. He's a combination of the Earth-616, Spider-Man: TAS, Ultimate Marvel, and Movie versions.
 * Franklin "Foggy" Nelson: Matt Murdock's best friend and business partner, sharing with him the Nelson & Murdock law firm.
 * Karen Page: The secretary at Matt Murdock's and Foggy Nelson's law firm.
 * Father William Everett: A priest that Matt Murdock confided in about his Daredevil persona, which he doesn't approve of, nor is he particularly fond of the costume. Based on the character from the movie Daredevil.
 * Luke Cage/Power Man
 * Daniel Thomas "Danny" Rand-K'ai/Iron Fist
 * William "Willie" Lumpkin: The Fantastic Four's mailman.
 * Courtney "Cory" Bonner-Davis: The Fantastic Four's fussy British landlady. She always complains about the Four. Based on the character from Fantastic Four: World's Greatest Heroes, with some traits from Ms. Lavina Forbes from the 90's Fantastic Four cartoon.
 * Foo-Foo: Cory's dog. He doesn't like the Thing.
 * Alicia Masters: A blind sculptor and the Thing's romantic interest.
 * Norrin Radd/Silver Surfer: Originally a young astronomer from the planet Zenn-La, he agrees to become Galactus' herald in return for the safety of his homeworld and the woman he loved. He's a combination of his Earth-616, Ultimate Marvel (Silver Searcher) and Movie counterparts.
 * Aunt Cass
 * Tadashi Hamada
 * Jonathan "Johnny" Blaze/Ghost Rider: A stunt motorcyclist who, in order to save the life of his father Barton, agreed to give his soul to "Satan" (revealed to be an arch-demon named Mephisto). He's a combination of his Earth-616 and Movie counterparts.
 * Eric Brooks/Blade: A dhampir vampire hunter. Known to the vampire underworld as "The Daywalker". He's a combination of the Earth-616, Spider-Man: TAS and Movie versions.
 * Abraham Whistler: A vampire hunter who took on a young Blade and trained him in martial arts and as a vampire hunter. His wife and two daughters were killed by a vampire. He's a combination of the Spider-Man: TAS and Movie versions.
 * Howard the Duck: An anthropomorphic duck from an alternate universe called Duckworld. He refuses to wear pants, and doesn't care if a certain animation company sues him.
 * Beverly Switzler: Howard's human girlfriend and a former model.
 * Namor McKenzie/Sub-Mariner: Ruler of Atlantis. Son of human sea captain Leonard McKenzie and Princess Fen.
 * Lady Dorma: Namor's wife. Despite her appearance as a demurely elegant aristocrat, she can be a fierce warrior-woman when the need rises. She dislikes Sue Storm.
 * Kevin Plunder/Ka-Zar
 * Shanna O'Hara/Shanna the She-Devil
 * Matthew Kyle Andrew Plunder
 * Zabu

HYDRA
HYDRA is a terrorist-military organization bent on world domination that was founded shortly after the rise of Nazism in Germany as the scientific branch of the Nazi Schnutzstaffel.


 * World War II Era Members
 * Johann Schmidt/Red Skull
 * Dr. Arnim Zola
 * Heinz Kruger
 * Vincent Beckers


 * Modern-Day Members
 * Baron Wolfgang von Strucker: The current leader of HYDRA.
 * Reinhardt/Daniel Whitehall/Kraken
 * Alexander Goodwin Pierce
 * Ophelia Sarkissian/Viper/Madame Hydra
 * Keniuchio Harada/Silver Samurai
 * Jasper Sitwell
 * Brock Rumlow/Crossbones
 * Julien Beckers
 * Carl "Crusher" Creel/Absorbing Man

Hellfire Club
The Hellfire Club is an exclusive secret society that worships the Phoenix Force.


 * Sebastian Hiram Shaw: The leader of the Hellfire Club. He's also the owner of Symstemized Cybernetics Lab.
 * Dr. Shinobi Shaw
 * Emmeline Grace "Emma" Frost/White Queen: see X-Men

Brotherhood of Mutants

 * Erik Magnus Lehnsherr/Magneto
 * Raven Darkholme/Mystique: A mutant with the ability to shapeshift. Rogue's foster mother and Nightcrawler's biological "father".
 * Victor Creed/Sabretooth: Logan's half-brother, and an ex-fellow soldier.
 * Mortimer "Mort" Toynbee/Toad
 * John Allerdyce/Pyro
 * Cain Marko/Juggernaut
 * Frederick J. "Fred" Dukes/Blob
 * Dominikos Ioannis Petrakis/Avalanche
 * Irene Alder/Destiny: A mutant precognitive able to accurately predict future events. She's Mystique's best friend and lover, and Nightcrawler's mother. She helped took care of Rogue before she joined the X-Men.

Morlocks

 * Callisto
 * Annalee
 * Ape
 * Caliban
 * Erg
 * Glowworm
 * Masque
 * Mole
 * Mark Hallett/Sunder
 * Tar Baby
 * Tommy
 * Jimmy Dorian/Leech
 * Torpid: Based on the character from X-Men: Evolution.

Weapon X
Originally known as Team X, the Weapon X program is a clandestine government genetic research facility project headed by Colonel William Stryker. It was at the Alkali Lake Weapon X facility where Wolverine's skeleton bonded with adamantium.


 * Colonel William Stryker Sr., M.D.: The leader of the anti-mutant conspiracy within the U.S. Government. He is under a belief that he is destined to eradicate "mutant threats" and that he has been ordained by God to do so, a trait he passed on to his son. He's a combination of the Ultimate Marvel version and movie version of William Stryker Jr..
 * Professor Andre Thorton (real name Truett Hudson): The man who lead the scientists that grafted Adamantium onto the bones of Wolverine, Sabretooth, and the others to create Canada's own super-soldiers. He later had his hand cut off by Wolverine.
 * David North/Christoph "Christopher" Nord/Maverick/Agent Zero: Colonel Stryker's second-in-command and a superhumanly accurate sniper/assassin. He's Asian-German. He's a combination of the Earth-616 and Movie versions.
 * Jason Stryker/Mutant 143: Son of William Stryker Jr. and grandson of William Stryker Sr.. A mutant with the ability to create illusions in the minds of others. He was lobotomized by his grandfather when he used his powers to torture his parents, causing his mother to commit suicide.


 * Former members
 * John Wraith/Kestrel
 * Kayla Silverfox

Ten Rings
The Ten Rings is a terrorist group led by the Mandarin.


 * Xin Zhang/Mandarin: The public leader of the terrorist cell bent on world domination known for his magical rings. He is a descendant of an ancient vicious Chinese dynasty that claimed to have relations to Genghis Khan. He's a combination of the Earth-616 and Marvel Action Hour versions, with Trevor Slattery's portrayal added to the mix.
 * Wong-Chu: A self-styled warlord and devoted follower of the Mandarin. He's half-Vietnamese, half-Afgahni. He led a group of terrorists that abducted Tony Stark. He killed scientist Ho Yinsen. He himself was killed by the Mandarin for allowing Tony Stark to escape. He's a combination of the Earth-616 and The Invincible Iron Man versions, and Raza.
 * Abu Bakar


 * Prometheus International
 * Taki
 * June
 * Li

Hulkbusters

 * General Thaddeus E. "Thunderbolt" Ross
 * Brigadier General Glenn M. Talbot: The right hand man of General Ross. He has a romantic interest in Betty Ross, but she constantly rejects him because he does not do a good job of hiding his disdain for either Bruce Banner or the Hulk. Though he's loyal to General Ross, he often has more common sense in comparison.

Masters of Evil

 * Emil Blonsky/Abomination: see Other Villains
 * Ivan Antonovich Vanko/Whiplash
 * Franklin Hall/Graviton
 * Georges Batroc the Leaper
 * Donald "Donnie" Gill/Blizzard
 * Marcus Daniels/Blackout
 * Paul Pierre Duval/Grey Gargoyle
 * Hypnotia: She has the ability to fascinate anybody and hold them to her will, even females. Dreadknight and Whiplash constantly compete for her affections, but she's seems to be attracted to Tony Stark. Based on the Marvel Action Hour version, with a bit of DC Comic's Godiva from Superman/Batman "With a Vengeance!" story arc in the mix.
 * David Cannon/Whirlwind

Hammer Industries
Hammer Industries is run by Justin Hammer, Tony Stark's business rival.


 * Justin Hammer, Sr.: The CEO of Hammer Industries. He's rivals with Norman Osborn and Oscorp's main competitor. Based on the Earth-616, Marvel Action Hour, and the Ultimate Marvel versions.
 * Justin Hammer, Jr.: The son of Justin Sr., born in the south of the US. A rival to Tony Stark. Based on the MCU version.

Jotuns
The Jotuns, also known as the Frost Giants, are the inhabitants of Jotunheim.


 * Laufey: King of the Frost Giants, and Loki's father.
 * Loki Laufeyson

Kree Empire

 * Supreme Intelligence: The leader of the Kree Empire.
 * Ronan the Accuser
 * Korath the Pursuer

Skrull Empire

 * Kl'rt/Super-Skrull

A.I.M.
A.I.M. (short for Advanced Idea Mechanics) is the organization of brilliant scientists dedicated to the acquisition of power and the overthrow of all world governments by technological means.


 * George Tarleton/MODOK (Mechanized Organism Designed Only for Konquest): Former A.I.M. scientist and current leader. He's a combination of his Earth-616, Marvel Action Hour, Avengers: EMH, and the Iron Man 3 video game counterparts, with a bit of MCU Aldrich Killian (pre-cured).

Dark Elves
The Dark Elves hail from the world Svartalfheim.


 * Malekith the Accursed
 * Algrim the Strong/Kurse

Oscorp

 * Norman Osborn/Green Goblin: A corrupt industrialist and scientist who is trying to perfect the Super Soldier drug for S.H.I.E.L.D., an obsession that leads to the neglect of his wife and son Harry Osborn.
 * Gustav Fiers: A mysterious man in the shadows with ties to Oscorp and the Parkers.

Sinister Six
The Sinister Six are a group of villains who share a hatred for Spider-Man.


 * Dr. Otto Gunther Octavius/Dr. Octopus (leader)
 * Aleksei Mikhailovich Sytsevich/Rhino
 * Adrian Toomes/Vulture
 * Sergei Nikolaevich Kravinoff/Kraven the Hunter
 * Quentin Beck/Mysterio
 * Maxwell "Max" Dillon/Electro

Trask Industries

 * Bolivar Trask: The architect for the U.S. Government 'Sentinel Initiative', a response to Magneto's terrorist attacks.
 * Sentinels: Massive mecha built to hunt down and kill mutants on the streets.

Other Villains

 * Thanos
 * The Other: A mysterious being that acts as an envoy for his master Thanos. Based on the MCU character.
 * Nebula
 * Chitauri: An offshoot race of the Skrulls. Though the Skrulls disclaim any relations with them. The Chitauri further evolved into different subraces.
 * Leviathans: Colossal beasts used as weapons and troop transports during the invasion of Earth by the Chitauri.
 * En Sabah Nur/Apocalypse
 * Horsemen of Apocalypse
 * Death
 * Famine
 * Pestilence
 * War
 * Senator Robert Edward Kelly
 * Wade Winston Wilson/Deadpool
 * Yuriko "Yuri" Oyama/Lady Deathstrike: The daughter of Japanese crime lord and scientist Lord Dark Wind (Kenji Oyama). She once had a relationship with Wolverine. Now she has an obsession of killing him, in a twisted way of righting the wrong of the theft of her father's theories and to restore her family's honor. She received extensive cybernetic enhancements including adamantium bones and talons, which would allow her to have her revenge. She becomes a mercenary and joins the Reavers.
 * Reverend William Stryker, Jr.: Son of Colonel William Stryker Sr. and father of Jason Stryker. A religious man who is convinced that Satan has a plot to destroy humankind by corrupting prenatal souls, the result of this corruption being mutants. He becomes the leader of the Purifiers, an anti-mutant coalition wearing almost Crusader-esque type outfits. He comes to see the birth of his mutant son as a sign from God, directing him to his true calling: ensuring the eradication of all mutant, a trait passed on from his father. He's a combination of the Earth-616 and Ultimate Marvel versions.
 * Nathaniel Essex/Mister Sinister
 * Obadiah Stane/Iron Monger: The CEO of Stane International, and was a friend and business partner to Howard Stark.
 * Fin Fang Foom
 * Dr. Samuel Sterns/Leader: A British ex-professor who got thrown out of the university after testing his "British Enhancile Program" on himself, gaining psychic and mental abilities, which also gives him green skin and enlarged his cranium. Abandoning his true human name, Sterns instead began to refer to himself as the Leader. He planned on creating an army from Gamma Radiation to help him take over the world using a special "Gamma Orb".
 * Yuri Topolov/Gargoyle: A Soviet scientist who became the first foe of the Hulk. An atomic accident caused by working with radiation mutated him into a grotesque, large-headed dwarf of extremely high intelligence. He allies with the Leader in order to find a cure for his mutation. He develops a creepy attraction to the She-Hulk.
 * Emil Blonsky/Abomination: A Russian-born English soldier who wanted to relive his glory days and volunteered to go through an experiment by Thunderbolt Ross (acting under the orders of his superiors). He was injected with a sample of the Super Soldier Serum to combat against the Hulk. Soon after, he rampage the city until he was stopped by the Hulk the first time.
 * Dr. Brian David Banner/The Father: The abusive father of Bruce Banner, and a genetic researcher who worked under General Ross in hopes of recreating the Super Soldier Serum. As much as he hated Bruce, he believes the Hulk as his "true son".
 * Brian Talbot: Glenn Talbot's younger brother and a colleague of Betty Ross. A former military officer-turned-bio-science executive at a company that is also a politically powerful Defense Department contractor. Based on the 2003 Hulk version of Glenn Talbot.
 * Dr. Curtis "Curt" Connors/Lizard
 * Herman Schultz/Shocker
 * Dmitri Smerdyakov/Chameleon
 * MacDonald "Mac" Gargan/Scorpion
 * William Baker/Flint Marko/Sandman
 * Edward "Eddie" Brock, Jr./Venom: Peter Parker's childhood friend turned rival at the Daily Bugle. Brock encounters an alien Symbiote, and bonds with it to become Venom. After learning that Parker is Spider-Man, he seeks revenge against Spider-Man for ruining his life.
 * Taneleer Tivan/Collector: One of the Elders of the Universe.
 * Carina
 * Dr. Viktor von Damme/Doctor Doom: Former science colleague of Reed Richards, now billionaire entrepreneur and CEO of Von Damme Industries. He also had feelings for Susan Storm. He funded Richards' space exploration to a strange cosmic dust cloud, which caused the ship to crash and caused the scarring of von Damme's face. Adopting a metal mask and a green cloak to hide his scars and his transformation, he calls himself Doctor Doom. He blames Richards for the accident, losing his money and company, and for "stealing" Susan from him. He returned to Latveria, and in six months turned the country around. He is revered by the citizens, who refer to him as "the good doctor".
 * Doombots: Doctor Doom's robotic replicas.
 * Ultron: Originally a group of robots designed by Hank Pym to be expendable super soldiers. They are rejected because of Pym's poor personal performance, so he reprogrammed them to be his servants. One unit (identified as Ultron-5) developed an independent mind and emotions, and its first shocking ultimatum upon gaining consciousness was to declare the human race its enemy. Seeting out to exterminate all life on the planet, the unstable and emotional Ultron seeks to upgrade its mechanical body to an ultimate, unstoppable form. With an army of robotic drones and the ability to enter and corrupt any computer network, Ultron will stop at nothing to see humanity wiped out.
 * Harvey Rupert Elder/Mole Man
 * Wilson Fisk/Kingpin: The head of New York corporate crime, a ruthless murderer and notorious for bribing his way out of any prosecution.
 * Dennis "Spike" Carradine: The burglar who shot Ben Parker. He was formerly the leader of a street gang called the "Skull", and once in the employ of the Kingpin.
 * Calvin Zabo/Mister Hyde: Quake's human father.
 * Raina
 * Mephistopheles: Known as Mephisto, a demon who rules his own infernal dimension. He is responsible for turning Johnny Blaze into the Ghost Rider and imprisons the soul of Doctor Doom's mother Cynthia von Damme.

Heroes of Tomorrow

 * Next Avengers aka A-Next: Many of these are children of the original Avengers and other heroes.
 * Steven "Stevie" Rogers, Jr.: Son of Steve Rogers/Captain America and Sharon Carter/Agent 13.
 * Henry Pym, Jr./Yellowjacket: Son of Henry Pym/Ant-Man and Janet van Dyne/Wasp. Based on his Next Avengers: HOT counterpart.
 * Azari T'Chaka/Panther: Son of T'Challa/Black Panther and Ororo Munroe/Storm. Based on his Next Avengers: HOT counterpart.
 * Rachel Anne Summers: Daughter of Scott Summers and Jean Grey-Summers. She inherited her mother's vast telepathic and telekinetic talents.
 * May "Mayday" Parker/Spider-Girl: Daughter of Peter Parker (Spider-Man) and Mary Jane Watson-Parker, who named her after her father's Aunt May.
 * Namorita: Daughter of Namor and Lady Dorma.