User blog comment:Jaga 321/Comics help 101/@comment-2058272-20150302233744

Earth-616 is fine, besides a few things (the Clone Saga, One More Day... drawn out story arcs like that which really overstay their welcome, and other infamous runs on classic characters... I'm sure you can hear about those on the internet, though... just ask anyone), and the only things I recommend for Earth-1610 are Ultimates 1, Ultimates 2, Ultimate Hulk Vs. Wolverine, and all of Ultimate Spider-Man.

I recommend reading the classic comics first, and then maybe skipping a few years to just the highlights of the past few decades, and then the modern runs...